Naltrexone For Multiple Sclerosis Information
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How does Low Dose Naltrexone help multiple sclerosis? How long does it take to see benefits of low does Naltrexone? Is this a worthwhile treatment for MS, a disease without a cure?

bob replied: "Naltrexone comes as a tablet to take by mouth. It usually is taken once a day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take naltrexone exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Naltrexone helps decrease the craving for narcotics or alcohol but does not treat addiction. It is important that you attend all counseling, support group meetings, and other treatments prescribed by your doctor. Take naltrexone regularly. Do not stop taking it without talking to your doctor. If, in the past 7-10 days, you have taken opioids (morphine, codeine, or others; ask your doctor or pharmacist for more information), tell your doctor before taking the first dose of naltrexone. Naltrexone will cause withdrawal if you have opioids in your blood. Your doctor may perform a challenge test before you begin taking naltrexone. A small dose of naloxone (a drug similar to naltrexone) will be injected into your vein or under your skin, and you will be watched for symptoms of drug withdrawal. If you have symptoms, you will need to wait a few days before beginning naltrexone. You should take naltrexone as directed by your physician. If you take heroin or any other opioid in small doses, you will not perceive any effect. Do not take large doses of heroin or any other narcotic; you may die or sustain serious injury, including com"

Mr. Peachy replied: "I would email and ask this lady for her opinion:"

pcheesewhiz replied: "I have been taking LDN for my MS for seven months now and realized a benefit from it less than a week after taking it. The first thing that happened was that my energy level increased. I spent four years sitting on the sofa or in bed sleeping due to my low energy levels. But now I work a part time job, mow the lawn, work out at the gym twice a week, hike, bike and have a social life. My symptoms which included greatly reduced balance, intense tingling, cramps, headaches, insomnia, depression, intense reactions to heat and cold, rigidity in the limbs have all been far, far less troublesome. The only thing that LDN has not improved is my optic neuritis. I feel as though I have my life back. Any anecdotal evidence that I have seen shows that about 80-90% of people with MS who have taken LDN have experienced some degree of relief. You are welcome to email me. And check out ldn.org. Take care and good luck."

r j replied: "I have no experience with this Medication, but I did find this website..I would take the info to your Neurologist and see what He/She thinks of it..."

teddys0180 replied: "I read in an article that naltrexone helps with alcoholism, not sure what MS though?"

How can I get a prescription for LDN (Low Dose Naltrexone) for Multiple Sclerosis if my neuro won't prescribe? It is not FDA approved for treating MS, but I have found a great deal of people who have MS are on it. How were they able to get the perscription?

harry l replied: "Only here>"

pcheesewhiz replied: "I took all the info I could gather on LDN and took it to my neurologist. She then gave me a prescription. Ask your GP if he/she will prescribe it for you. I only go to doctors who are open-minded. Any doctor who insists on calling all the shots, I fire. I tell them to their face that I don't like them. LDN works for me. It gave me my life back.The FDA meds did nothing for me."

Has anyone used Low Dose Naltrexone for Crohns or Multiple Sclerosis? I know people have used it, but I am looking for personal experiences with it.

pelops_dl replied: "A google search will profide a number of anecdotes, but those really won't give you a good idea of what you need to know. Your best bet is to talk to your doctor and ask him/her about the side effects, and efficacy. What does the scientific literature (journal articles) say as a whole? This is something your doctor may even have to research to find out for you. That's far more useful than asking for anecdotes. It is also the best way to arrive at an answer that is in line with the facts."

pcheesewhiz replied: "Your doctor will probably be useless in helping you get any kind of handle on the facts about Low Dose Naltrexone. There is money to be made when doctors prescribe medicines for which the patents have not expired. This is not the case with Naltrexone which has been on the market for almost a quarter of a century. Since your doctor gets his or her info on drugs from the drug reps, they will not be educated about Naltrexone. I have been taking Low Dose Naltrexone for multiple sclerosis for three and a half years now and it has given me my life back. Prior to taking it, I was on Copaxone and spent the day going from the bed to the sofa and then back again. In short my life was a living hell. Once I started taking Low Dose Naltrexone, I went back to work and the gym and began to have a social life again. Not everyone who has MS experiences as good a result from Copaxone as I did, but many do in fact have a very positive experience with it. You need to be on the correct dosage of 4.5 milligrams (unless you have spasicitity in which case you need to stay at 3.0 milligrams) and stay on it for at least three months to get the maximum benefit. I do not know the correct dosage for Crohns or any of the other autoimmune diseases-just the correct amount for MS. Keep in mind that that LDN cannot reverse the damage to the myelin. So the LDN will have no effect on any symptom that is the consequence of myelin damage. Your doctor gets no training in parmaceuticals in medical school. IT is just not part of the curriculum. Drug reps are the ones who educate the doctors on what to give thier patients. Drug reps are rewarded on the basis of promoting the drugs that have the highest profits. These are the drugs that are the newest that still have a patent. Drug companies openly discouage their reps from recommending anything other than drugs upon which they have a patent. They do this by giving bonuses and the highest salaries to the reps who do the best job at promoting the high dollar drugs. Conversely, reps who don't do this are either getting horrendous evaluations or they are already fired. Doctors are also given bonuses by the pharmaceutical companies on the basis of the drugs they prescribe. As a consequence of the aforementioned, may I suggest that you do your own research. Simply go to LDN.ORG and you will find many, many web sites that have infor on the drug and the various auto-immune diseases for which it is effective. Keep in mind that all the current research indicates that more research needs to be done. This is because giving any drug the total green light always means that they will not get another contract to do research on that drug. In other words approving a drug would only put them out of another job. Keep in mind also that drugs usually get approved because the drug company is trying to get apporval for them so that they can get a patent. But since Naltrexone was approved for the treatment of drug and alcohol abuse years and years ago, the patent has expired and therefore the drug companies cannot make big money on it. Since they cannot make the big money now on it, they will not put one penny into doing any research to get it approved for another use although it has the possibility to improve the lives of hundreds of thousends of people. They are in this for profit and could not care less about humanitarian purposes. Sad, isn't it?"

Multiple Sclerosis & Naltrexone? Does Naltrxone really help MS? If so, how? Is it possible to get a prescription or is it only prescribed for substance abuse? Is it like methadone? Once you're on it, can you get off it?

aminoguy replied: "You should always explore the idea that your MS could be mercury toxicity and try using N-Acetyl Cysteine, Vitamin A,C and E, Selenium, co-enzyme Q10, and Vitamin B-6, 12 and Folic Acid first. You also might want to try Oganic Germanium or GE-132 as it will probably be a bit cheaper."

Country Hick replied: "Low dose naltrexone (LDN), where the drug is used in doses approximately one-tenth those used for drug/alcohol rehabilitation purposes, is being used by some as an "off-label"* experimental treatment for certain immunologically-related disorders, including HIV/AIDS, multiple sclerosis, Parkinson's, cancer, autoimmune diseases, and central nervous system disorders. *Off-label use is the practice of prescribing drugs for a purpose outside the scope of the drug's approved label, most often concerning the drug's indication. In the United States, the Food and Drug Administration (FDA) requires numerous clinical trials to prove a drug's safety and efficacy in treating a given disease or condition. I would suggest talking to a physician or pharmacist about its availability by perscription and if it is available for use in treatment of immunological-related disorders yet."

stevancremeans replied: "A MUST READ IF YOU HAVE MS, HIV/AIDS, CANCER, AUTOIMMUNE DISEASES, AUTISM AND/OR CENTRAL NERVOUS SYSTEM DISORDERS: When I was diagnosed with Multiple Sclerosis, I thought my life was over. When they told me I had to take shots for the rest of my life, I wanted my life to be over. Then I found out about Low Dose Naltrexone! (LDN) No more shots! I have my life back! I feel great! If you are reading this, it's probably because you either have MS, or one of the diseases listed above. If you love or know someone who has MS, Please visit any of these free sites for more information. It may be just what you need. Each site is a good place to start. All LDN sites are non-profit."

pcheesewhiz replied: "Naltrexone is not addictive. It is a drug that blocks the effects of narcotics and was developed to help addicts recover. It has no side effects. No, it is not at all like methadone as it is non-addictive. It is not just prescribed for drug abuse. It is used by people who have auto-immune diseases. If your doctor is open minded, he/she will prescribe it. I took all the data on this drug to my neurologist. She read it and then was willing to write a prescription. Yes, many people who have MS take this drug and find that it works far better than anything else. I suggest you go to to see what people who have MS have to say about this drug. The FDA has not approved this drug for use by people with MS or any auto-immune disease because no drug company has submitted data that proves it is beneficial to them. The reason that this has not been done is that there is no money in it. The drug is currently generic and available at a fraction of the cost of current MS drugs. My very best to you."

Anyone now anything about the benefits/risks of taking low dose naltrexone (ldn) to treat multiple sclerosis? Thanks bella, but the cannabis won't work for me since it is my daughter that has been diagnosed (she may like the idea though, but she is only 15)

bella replied: "I don't know about that, but I am in school to be a nurse, and I had to learn about the terrible affects on the body that MS creates, it truely is sad, but I found out.. you can look it up also, check out some medicinal journals. *EDIT- Well, good luck in finding something to treat it, I just wanted to comment, that in a few years when she is old enough, if she wants to try it, I would suggest measuring out a small amount and baking with it (you can look up how to make canna-butter), then she would avoid the tar associated with smoking it, and would be able to strictly control how much she would be consuming (so she would be able to live normally without being 'stoned oblivious'), which is hard to tell when smoking also."

abacaxitoo replied: "The risks woud be minimal, because the dose is extremely low, but there's currently no solid proof of benefit. I searched PubMed (lots of medical journals) ... and couldn't find any clinical research supporting it, or even mention of a clinical trial. Right now, it's all "anecdotal" and with the variable course that MS follows it would be hard to tell if the naltraxone was doing something or if there was a remission. The only publication mentioning it was "Medical Hypotheses", which is where some really wierd stuff is proposed ... it'ssortof the X-Files of medical journals. It's being studied in Crohn's disease (clinical trial in progress)."

joe s replied: "rec girl, try visiting this forum. this is where I obtain most of the info on LDN including testimonials and progress etc etc. It was actually thru this very forum that I found a doctor that was able to prescribe me some just yesterday. I can't wait to get on the stuff....good luck to you. "

eilonwy82971 replied: "Here's some info on several things, LDN is listed first. Low dose naltrexone (LDN) just finished a Phase III clinical trial for use in MS last Nov. But articles were already coming out 2 mos. before that saying more clinical trials are still needed for use in MS. There are several clinical trials at various stages studying antibiotic therapy and MS. Reports published in 2006/2007 showed initial benefits with Sativex (cannabis). However, reports published in April from the latest trials showed Sativex was no more effective in treating MS pain than a placebo given to half the patients. It has been approved for use in Canada and is still development in Europe and the US. I was at an MS symposium in March, as far as any oral meds for MS there are a few, but they are still a few years down the line. There are 3 in Phase II Trials (to evaluate the effectiveness of the drug for a particular disease and to determine common short-term side effects and risks). There are 3 in Phase III Trials (to evaluate the overall benefit-risk relationship of the drug and provide a basis for physician labeling). I'm a nurse with MS. I spent a great deal of time talking with my doctor and reviewing the literature to decide which drug was best. Copaxone is a shot everyday but no flu-like symptoms. Because I have two very active children (2 and 4), along with still working part-time, I chose Copaxone so as not to have flu-symptoms. Copaxone is an expensive drug, but my insurance covers it, so I pay $15/mo. There are days I don't want to "shoot up", and in all honesty I skip a day about once a month, a small reprieve. But I know I will get through it, even if I don't get used to it."

Any one else taking low dose Naltrexone? I take 3.0 mg of Naltrexone for my Multiple Sclerosis. Anyone else take Naltrexone for their MS?

matt replied: "Im assuming its for the pain associated with MS but your doctor shouldn't be giving you naltrexone for MS. Naltrexone is an opioid antagonist (which means it binds to the opiate receptors in your brain preventing opioid agonists from having an effect) mainly used for alcohol and opiate dependence. For pain you would need an opioid agonist such as hydrocodone, morphine, oxycodone etc."

kensi replied: "I have read articles how low dose of Naltrexone would relieve pain in diseases like MS, fibromyaliga, etc. I think you would have to take it in addition to opiates? But it has been shown to be effective.. there's also ULTRA low doses, like 1mg or 0.5 mg that helps to reliever chronic pain."

Margaret replied: "Many thousands of people all over the world use low dose naltrexone (ldn) for autoimmune diseases like MS with great success. I use it for rheumatoid arthritis and am thrilled to bits. Ldn appears to regulate the immune system. This means the immune system is able to fight the disease - ldn plays no DIRECT role in this fight. Most people find that at the very least, ldn stops the progression of the disease. Many people are lucky enough to enjoy some improvement. "

Do you have multiple sclerosis? Have you tried LDN? Please tell me your experience with low-dose-naltrexone. Thanks J: Thank you for letting me know this info about Lyme and MS symptoms. I do not have MS - my dear niece does and I have read so many wonderful stories about LDN that she finally got her neuro to prescribe it yesterday. Now, I find the Lyme thing very intriguing....Both Lyme and MS are very exclusive to the Northern Hemisphere - could there be a lot of misdiagnoses? My niece is only 29 years old and recently had a mild heart attack, even though she doesn't fit the profile for one. I went online and read that Lyme can eventually cause heart disease/heart attack !! I am going to pass this info on to her. Dear pcheesewiz: Thank you so much for your input. I am glad that this is helping you! I was reading last night that some doctors in Europe postulate that MS is actually Lyme disease - maybe everyone should get tested.

. replied: "I have MS, but never heard of LDN. Thanks for asking this question. I'm making an appointment with the neuro tomorrow morning and asking about this. I hope you are doing well."

eilonwy82971 replied: "Low dose naltrexone (LDN) finished a Phase III clinical trial for use in MS in Nov. '08. But articles were coming out already in Sept. '08 saying more clinical trials are still needed for use in MS. At an MS Symposium this spring, as far as any oral meds for MS there are a few, and there is hope they'll be ready by the end of '09. There are several clinical trials at various stages studying antibiotic therapy and MS. Reports published in '06/'07 showed initial benefits with Sativex (cannabis). However, reports published last month from the latest trials showed Sativex was no more effective in treating MS pain than a placebo given to half the patients. It has been approved for use in Canada and is still development in Europe and the US. The best advice I have is to have great communication with the neurologist!"

J replied: "Hello~ My daughter was prescribed LDN but never had an opportunity to take it...However many other Lyme patients we know have taken it and done very, very well with it..helped the sludgy cognitive issues and the severe fatigue! (As you probably already know, many to many MS symptoms are identical to MS but almost all treatments are the opposite, save this one and some other brain fog ones) BTW, have you recently explored the relatively high possibility of Lyme induced MS? If not, please see the following science based web sites (can't hurt to look and process): Or: The following websites explain why neurologists do not understand Lyme induced MS (Fraudulent guidelines by IDSA and the AAN was right there with them!!!)-(Anotherwords, it's not the individual doctors, it's the guidelines they must abide by and blindly believe in) I hope I have not aggravated you...not meant to , just want to bring up to date the viable possibilities. Best wishes~"

pcheesewhiz replied: "I have multiple sclerosis and I take LDN. Prior to taking LDN I spent my days on the sofa because I had so little energy. I was exhausted all the time and had symptoms that changed every three or four months. Once I started taking LDN, all that changed. I was able to go back to having a relatively normal life. I have the energy to work out at the gym, take care of my home and enjoy a social life as well as working a part time job. My neurologist prescribes LDN to many of her MS patients to manage their symptoms."

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