Avandia And Pcos
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Top Questions and Answers
I have pcos and desparately want to have a baby? i have no cycstics in my ovarians but the doctor says i have it (pcos)I was on mediformin but it didn't work.now the doctor has me on clomid 50mg just waiting for my period.also avandia daily i waited 6 years to have a baby i hope this helps me out i need to know if this has worked for anybody to conceive my husband got his sperm checked he was ruled out. i had to take provera for 7 days to get a period now i am just waiting for it but i never tried clomid so on the first day l start

green eyes replied: "i have the same thing, however i took metformin for only 1 month.. I am now months pregnant.. have they checked your husband to see if he is ok? maybe his sperm count is too low.. they should run other test on both you and him. good luck."

auskan2002 replied: "I'm not sure about being on clomid just waiting for your period. Usually clomid is taken for the first 5 days of your cycle so something doesn't sound right."

T G replied: "some times clomid and timed intercourse is not enough the sperm may be having a hard time reaching your egg you may want to have your spouse get a semen analysis and look into having an IUI (Intra Uterine Insemination) they put a catheter with the sperm in it directly into your cervix greater chance of sperm meeting your egg it does not hurt and it can be done in a GYN office."

Melissa B replied: "I didn't have PCOS, but Clomid did work for me. I just read an interesting article about PCOS and low carb eating. Here's the link to the article. I found this interesting because a co-worker of mine had not conceived in 9 years. I wouldn't say she was really trying, more like not preventing. Her doctor suspected PCOS, but she didn't want to have any tests done. Well, she went on a low carb diet and lost about 80 lbs. within about 10 months. Then, suddenly she was pregnant. I know large women can get pregnant, and I'm not saying you must be overweight. I just think that with PCOS, maybe carbs do effect it. Perhaps removing some carbs from your diet may help the PCOS. Good luck!"

Donna replied: "IVF (in vitro fertilization) treatment; IUI, ICSI and Laparoscopic surgery is very cheap in India. The cost is very low and the medical services are very good in India. My cousin and her husband got their IVF treatment in India through the Forerunners Healthcare in India and is all praise for this company. She is a known case of PCOS.She is a very happy mother of a baby boy now. She just paid 2500 pounds for the full IVF treatment in India for which she was quoted 8000 pounds in private setup in UK. Forerunners Healthcare is very famous in India. I read a lot about them in the newspapers. I have also read about a Chinese couple who planned surrogacy through the Forerunners Healthcare. They arrange financing for USA, Canadian, UK and other international patients who plan to have surgery and infertility treatment like IVF, IUI, and ICSI abroad for low price. They also have photos pasted of their International patients. You can checkout their website. There are huge cost savings. As a doctor I personally believe that surgery and treatment can be easily handled in India, as the quality of healthcare available In India is simply best in the world. The surgeons are USA/UK trained and facilities are 5 star. Hope this helps."

Marcella G replied: "It sounds like your doctor is putting you through a normal course of treatment for someone with PCOS. These are additional things you should be aware of as you try. - eat a healthy diet, including replacing processed sugar and flour with whole grains and lower sugar items. Make sure you get plenty of vegetables. - remove caffiene from your diet - Use Astroglide or Preseed instead of KY Jelly as a lubricant, as KY can negatively affect sperm - exercise regularly (4-5x per week) - have sex every two days, instead of daily, this will maximize sperm count. Doing these things can improve the effectiveness of your treatment. Clomid is most effective in the first 4-6 rounds that it is given, so you will want to do what you can to make these months as effective as possible. Many people with PCOS have good results when combining Clomid and insulin sensitizers such as Avandia, Metformin or Actos. Good luck."

Anyone have PCOS and weight gain issues because of taking Metformin(Glucophage)? I have PCOS and have been treated with Avandia for the past 3 years. I had no side effects from the Avandia, and after 4 months of that and Clomid for 2 cycles I sucessfully conceived. Now I'm trying for child #2, and my endocrinologist has decided to add Metformin to the mix, saying it should better my chances, along with the Avandia, to become pregnant. In the first 2 weeks on the Metformin I gained 10 lbs, and in the past 3 months I have gained a total of 17 lbs. Nothing in my life has changed, just the fact that I'm taking the Metformin. I asked my doc about it, and he says that he doesn't believe that it's the med causing weight gain, and that it's good for me so he wants me to continue. Anyone have a similar experience with this med? If so, what did you do about it. I don't want to hinder my efforts for becoming preg, but I also don't want to gain any more weight. I'm already overweight as it is.

Rosey55 D replied: "All drugs that the regular doctor puts people on can cause weight gain."

mollyneville replied: "Sorry to hear that, dear. Usually metformin helps people LOSE a little weight, not gain it. Stay healthy, continue healthy diet/exercise, and hang in there! By the way, I AM a "regular doctor". Some meds ARE associated with weight gain, some can help with weight loss (not much) and many are weight neutral. There's nothing we don't want you to "know about". No great conspiracy. No secrets."

tygger in pa replied: "I get treated for PCOS w/ metformin as well... and it has actually subdued my weight.... not really loosing but not gaining either, before it however I was gaining like crazyyyy. My friend however, when she started taking hers she was Always hungry @ first. My prayers are w/ you."

jan replied: "my sister is a big girl and she takes it, it does not make her gain weight. in fact i think she lost weight."

Karla S replied: "I have PCOS also and I didnt' have weight gain but I was extremely ill on Metformin & was taken off of it. I see a Reproductive Endcronolgist by the way, not a regular OBGYN. Metformin is for those that are Insulin Resistant, but it will not help you ovulate, it will help get your insulin under control & help you lose weight (if you are overweight)."

beta_slave replied: "I am on it, but it makes me sick all the time and I lose weight instead of gain. I know what you mean about being overweight. I have PCOS, I am trying to conceive after having a miscarriage, and I am about 100 lbs. overweight. The glucophage usually helps people lose weight, but for some it doesn't. I have found that if I eat a strict diabetic diet I lose weight. You might want to give it a try."

Concerned about using Avandia!!!? I'm back from my second consult with the RE. After doing a month of tests, everything appears normal. However, he thinks my glucose might be too high (87) compared with my fasting insulin (4) and wants me to try Avandia to help regulate ovulation. Im really confused b/c neither of those numbers were flagged as high, and I do suspect I have irregular ovulation but have no signs of PCOS. My BIG worry is that Avandia is Category C in pregnancy, so wth!? I dont want to risk birth defects on what appears to be a shot in the dark. Anyone have any insight? I've also heard that it causes weight gain and my RE said he wanted me to gain 5 pounds which may be an ulterior motive of his. This is also nuts to me becuase I am 5'8" and 138 lbs-- hardly a waife! And it took me two years to lose the weight from my first pregnancy (concieved without help) so Im devastated at the thought of putting it back on. Any advice out there? I dont know what to do.

jilldaniel_wv replied: "I take avandia for ttc so maybe I can help a little. Eventhough it's a class c drug it's never been shown to cause any birth defects and your doctor will take you off it when you get a confirmed pregnancy test. It can cause weight gain and if your dr thinks you need to gain a few then try to do it healthfully."

Is weight gain and fat gained from Avandia treatment permanent? I have been taking Avandia for two weeks to treat PCOS. I have noticed fat increasing in areas where I never had fat before. I don't have a scale but I am assuming I am also gaining weight. I am wondering if this fat deposition and weight gain is permanent? I read that Avanida causes new fat cells to form, I wonder if that means that I will always have this new fat, even after stopping the pills? I think I will call my doctor tomorrow and switch back to metformin.

sue replied: "that isn't fat. It is water weight. go see the doctor immediately about this. It isn't good to have this problem. It will go away when you get off the avandia."

pcos and maybe pregnant? ok..I have a couple of cysts on my left ovaries.. PCOS basically..Have been taking medication-avandia and prenatal vitamins. for the past 3 months.. In December, I had my period on the 19th..January, it was on the 21st.. February, nothing... Do you think its possible I'm pregnant.. Only symptoms I am having are sore breasts and just late.. thanks.

bethanne_525 replied: "take a pregnancy test"

kjhall75 replied: "Of course it's possible. It wouldn't be too early to test now. Why don't you take a test?"

Confused as usual replied: "I have PCOS and the first sign I was preggers was sore breasts."

Kasey C replied: "Just having cysts on your ovaries doesn't mean that you have PCOS. I have PCOS, and have had it since I was 9 (now 24). Only a doctor can determine that you have PCOS. And many women will get a couple of cysts in their lifetimes, and have no inferility at all. Plus you cycle range seems fairly normal. I don't think that you have PCOS unless your doctor has told you so... so pregnancy willl be much easier for you. You have a great chance to be pregnant. I would recommend going to the doctor to get a blood test (it is better than just a home pregnancy test), but you can start with an over the counter kind. Some women also have no symptoms of pregnancy for months, so don't be worried that you might not have more of the common symptoms. If you are pregnant- Then Congrats!!!! If not, and you want to be, then good luck and keep trying. Some great places for online support are , and ."

using metformin to treat PCOS, how long does it take to start menstrating? I am a 30 yr old mother of 4 with PCOS. My last 3 children were conceived while taking avandia, which is no longer available due to side effects. I am now being treated with 1500 mg of metformin to try and get my cycle going. I have been on it for 2 months and nothing has happened. Each time with avandia i was only on it from 3 to 5 weeks before my cycles started. I am starting to wonder if this is going to work. How long should i keep waiting?

ZIGGY JR replied: "i got mine 3 weeks after starting but some woman may take up to 3 months to get there first period so i say if you dont get your period within 3 months of taking it call your doctor"

Stephanie replied: "I've had PCOS for years, since early teens. I'm going to be 24 here in a few days. I was put on the BCP and Metformin way back in the day. Been on it ever since I can remember. The Metformin never did help me with the cycles and to lose weight. Oh well. the BCP was was helped me with all that. I can't complain about the Metformin all that much tho, when I got off the BCP after getting married, it only took a month and a half for me to get pregnant. I'm about 10 weeks now. It's the only thing I was on when I got pregnant. So...in the end, it didn't help with my cyles back then, but maybe it did just recently? Not sure. Always used the combo together."

pcos and ttc? i just got diagnosed with pcos. my question is, in order to treat this i am supposed to take femara (similar to clomid) and Avandia. i have heard that Avandia is very dangerous as all drugs have a risk of serious side effects i have done some research on it and im scared to take it. it was listed as a diffective drug. so i guess my question is do you think that just taking the femara this cycle alone to ttc would work? or would it just be pointless without the Avandia? im not normally this concerned about a medication but the more i have learned about it i don't think it would be safe.

Row replied: "My suggestion is to discuss this with your doctor or get a second opinion. Some of these drugs can have crazy side effects. I wouldn't take them until your questions are answered."

T.L. replied: "I also have been diagnosed with PCOS. My DR. put me on Clomid and Metformin. The Metformin is great for PCOS in my opinion. It takes a few weeks to get used to it, but I would think it would be a better alternative if you are scared of the Avandia. Maybe you could ask your DR. if Metformin would be a better choice for you. Good luck."

MichiganGirl replied: "Femara has a much better chance of working in combination with insulin-sensitizing drugs, such as metformin. Avandia isn't usually prescribed for PCOS, metformin is. Metformin has the same effect, but is safer. Taking metformin for 3 months before starting the femara with give you a much better chance of conceiving, as long as you are taking between 1500-2550 mg of metformin per day. Also, staying on metformin throughout pregnancy gives you a normal miscarriage rate of 12%, versus 46% for those who don't take metformin during pregnancy. Good luck and baby dust*****:)"

Success stories with PCOS? i was diagnosed 4 months ago with pcos (ploycystic ovarian syndrom) . my hubby and i have been ttc for almost 3 years! and i was on avandia and femara for cycles and the doctor came to the conclusion that it wasn't stimulating my ovaries. so now he put me on metformin and when i start my period i will be taking clomid. any sucess stories with these meds? im starting to feel like its not going to happen! im trying to be patient and wait for God's timing but im just so frustrated. any sucess with clomid instead of femara? any would be great ladies!

dueoct16boy#3 replied: "I was diagnosed 10 years ago when I was 19 years old. I tried Clomid for awhile and it didn't help at all. Did other things but nothing was helping. I gave up on the medical ways and decided to research it more. Found out about the insulin resistance and the links to diabetes and that they recommend basically treating yourself like a diabetic so that is what I did. I started eating more non-starchy veggies and proteins and watched my high sugar fruits and didn't eat breads, pastas, sweets, rice, starchy veggies or drink sugary drinks and I ended up losing 50 lbs and regained my cycles on a more normal level and suddenly I became pregnant with my first son. When I eat to many of those "bad carbs" I gain weight and my cycles get messed up but if I watch what I eat I feel better and have more regular cycles. I am now 37 weeks pregnant with my 3rd son :-)"

shortysarmywife replied: "My friend got pregnant on the second month of just clomid. Im currently on my 2nd cycle of Clomid and the Dr thinks Im finally ovulating. We've been ttc for 34 months so I know how you feel. Hope it works for you as well. Lots of baby dust and prayers."

Cyndi replied: "I have no experience with these drugs, but I did suffer from PCOS all my life. It's so hard to diagnose. I wanted to congratulate you for having a doctor who recognized what PCOS is and didn't tell you that your symptoms were all in your head, like I heard for years. Good luck. There is hope. I had one son after 8 years of marriage, and another 5 years later, with no drugs. I hope your next post is one asking what to do about morning sickness!"

yelloweskimo replied: "My doctor identified a hormonal imbalance I have consistant with PCOS - higher male hormone, which was causing me not to ovulate and to have longer cycles. Because I was told it was only a mild case, she was reluctant to try any medications until I had been trying to get pregnant for 12 months without any luck - then I was to go back and see her. I decided to tackle the condition myself. I am not sure whether I have an insulin resistance that a lot of people with PCOS have, but read that an insuline-resistance diet helps those with PCOS with or without insulin-resistance, and the underlying cause of PCOS is insulin problems. Insulin regulates the sex hormones, if your body can't handle the insulin, your sex hormones get all out of wack - usually with greater presence of male hormone. This then causes anovulation. Anyway, I adopted an insulin-resistance diet and started taking minerals chromium, magnesium. manganese, and something else (can't remember), as these are proven to aid in regulating your body's insulin production and your resistance. The supplement I took was called 'sugar balance' by Blackmores, it is actually meant to aid in weight loss, but the ingrediants in it were consistant with the ones I wanted. I guess the point of it was to control insulin to aid weight loss. So after all this my cycles went from anout 55 days to 30 - 34 days and I started ovulaing again, I am now 24 weeks along. This was accomplished over about a 6 month period. I also added in some exercise good for insulin production and regulation. I honestly don't think I have the insulin resistance associated with PCOS, as I do not have the weight problems, but believe that this system would be beneficial to all people with PCOS. I suggest that you make these types of lifestyle changes - if you tackle the insulin problems head on, the rest of your body will follow, as insulin controls the production of a lot of other hormones within the human body."

Anyone else with PCOS and totally depressed?? Was on Metformin for awhile but made me so sick i couldn't leave the house. Switched to Avandia but made me gain tons of weight and insurance won't pay for that one!! Has anyone had any success with something else? Getting to the end of my rope and very discouraged. thanks

Katrina_Survivor24 replied: "I was diagnosed with PCOS and I am trying to get pregnant now. I stopped having periods for three years because of it. I just went to the doctor last week. First I had to take Provera to make my period start. After the fifth day of my cycle I start taking Clomid. If your trying to get pregnant ask you doctor about it. Anyways, yes it is depressing. If you need to talk about it you can e-mail me."

woooo18 replied: "Absolutely!!! Tried metformin but it did absolutely nothing! Also tried mefanamic acid for the period pain, but also no luck. Not plannin to have children at any point in time, and sometimes wish they'd just suck it all out, but i'm only 24 and apparently don't know what I want yet! Been given the pretty unattractive option of going through menopause early, but can't say i'd look forward to the chance of yet more body hair. Hope things are a little more successful for you, but I sympathise x"

steiny669 replied: "I was diagnosed with PCOS about 5 years ago and ever since I have been taking birth control pills to regulate the hormones ( I am taking ortho tricyclen) and it has been working wonderfully. My periods are normal and I have lost alot of weight."

appalachianhokie replied: "Are you on the pill? That made me depressed. I switched to a different pill and it helped a lot. But there is a proven connection between PCOS and depression--check out the link below. Also, I highly recommend. It's a message board for women with PCOS, and many of us are dealing with depression or have had it in the past."

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